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4.4 Activation of the reninangiotensin-aldosterone system and disturbances in calciumphosphate homeostasis Aberrant activation of the RAAS is a critical driver of CKD progression, contributing to glomerular hypertension, inflammation, and fibrosis

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Benzyl alcohol has been linked to a fatal "gasping syndrome" in newborns, so only preservative-free sterile water for injection should be used in that group

Therefore, M199 supplemented with 20 mM HEPES and 10% iFBS appeared to be suitable for incubation of NTS by vortex transformation and was used for the drug sensitivity assays